Ampr gene is responsible for developing resistance in
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Pesticide resistance in arthropods has been shown to evolve by two main mechanisms, the enhanced production of metabolic enzymes, which bind to and/or detoxify the pesticide, and mutation of the target protein, which makes it less sensitive to the pesticide. One route that leads to enhanced metabolism is the duplication or amplification of the structural gene(s) encoding the detoxifying enzyme, and this has now been described for the three main families (esterases, glutathione S-transferases and cytochrome P450 monooxygenases) implicated in resistance. More recently, a direct or indirect role for gene duplication or amplification has been described for target-site resistance in several arthropod species. This mini-review summarises the involvement of gene duplication/amplification in the insecticide/acaricide resistance of insect and mite pests and highlights recent developments in this area in relation to P450-mediated and target-site resistance.
The Ampr gene ,also known as Ampicillin resistance gene confers resistance to the antibiotic, Ampicillin.
These genes can be introduced into bacterial cells with the help of a plasmid( circular DNA) that acts like a vector in transforming the bacterial cells and making them ampicillin resistant.
Ampicillin acts by inhibiting cell wall synthesis in bacteria and therefore are bactericidal in nature.
In presence of the Ampr gene, an enzyme is produced that inhibits the action of Ampicillin and helps the bacteria to survive.