Question

At normal atmospheric pressure, what will happen to enzymes?

Answer 1

Enzymes are not affected by change in pressure

Answer 2

$\huge\mathfrak\color{blue}{Answer}$

Pressure decreases the enzymatic activity until complete inactivation occurs at 2 kbar. The inactivation is associated with changes in the rate-limiting step of the reaction caused by additional hydration of the active site upon compression and/or minor conformational changes in the active site region.