Chemistry, asked by sushil6916, 9 months ago

at the oxygen binding site of heamocyanin copper ion is coordinated to which ring in coordination complex​

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Answered by shubhamshivansh
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Hemocyanin

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Hemocyanins (also spelled haemocyanins and abbreviated Hc) are proteins that transport oxygen throughout the bodies of some invertebrate animals. These metalloproteins contain two copper atoms that reversibly bind a single oxygen molecule (O2). They are second only to hemoglobin in frequency of use as an oxygen transport molecule. Unlike the hemoglobin in red blood cells found in vertebrates, hemocyanins are not bound to blood cells but are instead suspended directly in the hemolymph. Oxygenation causes a color change between the colorless Cu(I) deoxygenated form and the blue Cu(II) oxygenated form.[1]

Hemocyanin, copper containing domain

Hemocyanin2.jpg

Single oxygenated functional unit from the hemocyanin of an octopus

Identifiers

Symbol

Hemocyanin_M

Pfam

PF00372

InterPro

IPR000896

PROSITE

PDOC00184

SCOPe

1lla / SUPFAM

Available protein structures:

Pfam

structures / ECOD

PDB

RCSB PDB; PDBe; PDBj

PDBsum

structure summary

PDB

1oxy :110-373 1nol :110-373 1lla :110-373

1ll1 :110-373 1hc1A:136-393 1hcyD:136-393 1hc6B:136-393 1hc4C:136-393 1hc3C:136-393

1hc5C:136-393 1hc2C:136-393

Hemocyanin, all-alpha domain

PDB 1hcy EBI.jpg

Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 angstroms resolution

Identifiers

Symbol

Hemocyanin_N

Pfam

PF03722

InterPro

IPR005204

PROSITE

PDOC00184

SCOPe

1lla / SUPFAM

Available protein structures:

Pfam

structures / ECOD

PDB

RCSB PDB; PDBe; PDBj

PDBsum

structure summary

Hemocyanin, ig-like domain

PDB 1oxy EBI.jpg

crystallographic analysis of oxygenated and deoxygenated states of arthropod hemocyanin shows unusual differences

Identifiers

Symbol

Hemocyanin_C

Pfam

PF03723

InterPro

IPR005203

PROSITE

PDOC00184

SCOPe

1lla / SUPFAM

Available protein structures:

Pfam

structures / ECOD

PDB

RCSB PDB; PDBe; PDBj

PDBsum

structure summary

Species distribution

The hemocyanin superfamily

Structure and mechanism

Catalytic activity

Spectral properties

Anticancer effects

Case studies: environmental impact on hemocyanin levels

See also

References

Further reading

External links

Last edited 6 days ago by Rjwilmsi

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