Autoimmune diseases are pathophysiological circumstances that outcome from loss of self-resistance and the subsequent immune obliteration of host tissues. Autoimmunity is interceded by an assortment of molecular and cellular events and reactions. The advancement of autoimmune diseases is an extremely complex process in which acknowledgment of self-antigens by lymphocytes is crucially engaged with pathologic organ damage. Autoimmune diseases are acquired as an intricate trait, with different loci controlling different aspects of diseases susceptibility.
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