BIOLO
cent) are o
hocytes ar
ence
کی
normally
1.3.2 Rh grouping
other antigen, the Rhantien similar to one present in Khem money
Rh), is also observed on the surface of RBCs of majority nearly 80
cent) of humans. Such individuals are called Bh positive (Phe)
luced fronde
those in whorn this antigen is absent are called Rh negative Rh-ve).
Rh-ve person, if exposed to Rhrve blood, will form specific antibodies
se a variety ainst the Rh antigens. Therefore, Rh group should also be matches
clotting ofore transfusions. A special case of Rh incompatibility (umiemasching
prve blood of the foetus. Rh antigens of the foetus do not get exposed to
he Rh-ve blood of the mother in the first pregnancy as the two bloods are
sell separated by the placenta. However, during the delivery of the first
hough ithild, there is a possibility of exposure of the maternal blood to small
mounts of the Rh+ve blood from the foetus. In such cases, the mother
starts preparing antibodies against Rh antigen in her blood. In case of
her subsequent pregnancies, the Rh antibodies from the mother (Rh-ve)
ers which
been observed between the Rh-ve blood of a pregrant mother with
.
.
en done.
ver the
leak into the blood of the foetus (Rhtve) and destroy the foetal RBCS.
ntigens
pis could be fatal to the foetus or could cause severe anaemia and
mely A aundice
to the baby. This condition is called erythroblastosis foetalis.
atural This can be avoided by administering anti-Rh antibodies to the mother
ution mmediately after the delivery of the first child.
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