Question

Briefly write on gout and xanthinuria in

Answer 1

Answer:

Xanthine oxidase is defined as an enzyme activity (EC 1.17.3.2).[4] The same protein, which in humans has the HGNC approved gene symbol XDH, can also have xanthine dehydrogenase activity (EC 1.17.1.4).[5] Most of the protein in the liver exists in a form with xanthine dehydrogenase activity, but it can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification

Answer 2

Causes. Gout is caused initially by an excess of uric acid in the blood, or hyperuricemia. Uric acid is produced in the body during the breakdown of purines - chemical compounds that are found in high amounts in certain foods such as meat, poultry, and seafood.