Question

Calculate the ATP and NADPH requirements for the synthesis of Lauric acid (C 12:0) from acetyl CoA * Your answer

Answer 1

Answer:

78 ATP

Explanation:

Assuming Lauric acid (12:0), then 78 ATP

Why 78?

First, it costs 2 ATP to add CoA to the fatty acid, giving lauroyl-CoA.

5 rounds of Beta oxidation produces 6 acetyl CoA, each worth 10 ATP = 58 ATP

Each round of Beta oxidation also produces reduction equivalents (FADH2 & NADH)

FADH2 = 2 ATP in ETC

NADH = 2 ATP in ETC

Total of 4 ATP per round (x5) = 20 ATP

58 + 20 = 78