Question

Challenges faced by bacteria if its capsule is removed?

Answer 1

Answer:

The capsule is considered a virulence factor because it enhances the ability of bacteria to cause disease (e.g. prevents phagocytosis). The capsule can protect cells from engulfment by eukaryotic cells, such as macrophages. A capsule-specific antibody may be required for phagocytosis to occur.

Explanation:

Answer 2

Answer:

The capsule is considered a virulence factor because it enhances the ability of bacteria to cause disease (e.g. prevents phagocytosis). The capsule can protect cells from engulfment by eukaryotic cells, such as macrophages. A capsule-specific antibody may be required for phagocytosis to occur.

Explanation:

Removing the capsule helps bacteria evade the antimicrobial peptides produced by epithelial tissue in the lungs as part of the innate immune response. Removing the bacterial capsule also sets the stage for more invasive infections by making it easier for pneumococci to invade epithelial cells and move into the blood.

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