Question

Clinical significance of spot urine protein creatinine ratio

Answer 1

According to the Kidney Disease Outcomes Global Improving clinicalGuidelines for Glomerulonephritis, spot urine protein/creatinine (P/C) ratioshould be used for monitoring LN. However, some reports write that therandom spot urine P/C ratio is unreliable in monitoring proteinuria in SLE glomerulonephritis patients.


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Answer 2

Answer:

This study revealed that spot urine PCR is a reliable estimate of 24HP value in patients with IgAN. In contrast, there is a considerable difference between the daily urine protein excretion amount based on a 24-h urine sample and that which is calculated from spot urine PCR in patients with NS.