Comment on a DNA protein interaction technique initially carried out in yeast.
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Analytical methods include microscopy and classical biochemical assays like chromatin immunoprecipitation analysis (ChIP), Systematic Evolution of Ligands by EXponential enrichment (SELEX), Electrophoretic mobility shift assays, DNA footprinting, and protein-binding microarrays.
The protein that are involved in these interactions can act as an enzyme that catalyzes the biochemical reactions. The protein contains specific DNA-binding domains that recognize specific DNA sequences and bind or wrap around DNA helix grooves.
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