Question

define beta thalassemia?​

Answer 1

Answer:

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define beta thalassemia_?

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Beta (B) thalassemia: B-Thalassemias are due to mutations in the HBB gene on chromosome 11, also inherited in an autosomal-recessive fashion. The severity of the disease depends on the nature of the mutation. Mutations are characterised as (8° or B thalassemia major) if they prevent any formation of $ chains (which is the most severe form of 8 thalassemia); they are characterised as (B or B thalassemia intermedia) if they allow some B chain formation to occur. In either case, there is a relative excess of a chains, but these do not form tetramers; rather, they bind to the red blood cell membranes, producing membrane damage, and at high concentrations they form toxic aggregates.

Answer 2

Explanation:

Beta thalassemia is an inherited blood disorder characterized by reduced levels of functional hemoglobin. Hemoglobin is found in red blood cells; it is the red, iron-rich, oxygen-carrying pigment of the blood. A main function of red blood cells is to deliver oxygen throughout the body

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