Question

Define biotransformation in pharmacology

Answer 1

Biotransformation means chemical alteration of chemicals such as nutrients, amino acids, toxins, and drugs in the body. It is also needed to render non-polar compounds polar so that they are not reabsorbed in renal tubules and are excreted.

Answer 2

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$\huge\text{\underline{Biotransformation:}}$


It is the chemical modification, which is made by an organism on a drug.


It is the chemical alternation of chemicals in the body, such as:


=> $\sf{\underline{Amino\:acids}}$

=> $\sf{\underline{Nutrients}}$

=> $\sf{\underline{Toxins}}$

=> $\sf{\underline{Drugs}}$


$\sf{\underline{\underline{Objectives:}}}$


⚫To inactive pharmacological effect.

⚫To enhance pharmacological effect.

⚫To convert pro-drugs into active drugs.


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