Define cell cycle. Describe various phases of cell cycle. Add a note on significance of mitotic cell division
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Cell cycle is a series of events that take place in a cell leading to the duplication of its DNA and the subsequent division of the cell to produce two daughter cells.
A cell cycle consists of two phases:
(i) a non dividing phase called the interphase
(ii) a dividing phase called M - phase or simply mitosis
INTERPHASE :
The two daughter cells produced from a mother cell are relatively small with a full sized nucleus but relatively little cytoplasm.These cells are said to be in interphase.During this phase , they prepare for the next cell division and grow to the same size and as their mother cell .
Interphase has three phases :
(i)First Growth Phase or G1 phase -
RNA and proteins are synthesised , the volume of cytoplasm increases . Mitochondria ( in animals ) and chloroplast ( in plants ) divides as tgey contain their own DNA.
(ii) Synthesis Phase or S phase -
More DNA is synthesised , the chromosomes are duplicated.
(iii)Second Growth Phase or G2 phase -
This is a shorter growth phase , in which RNA and proteins necessary for cell division continue to be synthesised .
MITOSIS :
Mitosis is the cell division in which one parent cell divides into two identical daughter cells. Mitosis occurs in somatic ( body ) cells and occurs throughout life.
Significance of mitosis :
The most important aspect of mitosis is that the same normal chromosome number is maintained at each cell division. In a mitiotic division full set of chromosomes is passed on each daughter cell . That is diploid 2n number of chromosomes. In humans 46 chromosome or 23 pairs of chromosomes are passed to two identical daughter cells.
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During the mitotic (M) phase, the cell divides its copied DNA and cytoplasm to make two new cells. M phase involves two distinct division-related processes: mitosis and cytokinesis. ... Mitosis takes place in four stages: prophase (sometimes divided into early prophase and prometaphase), metaphase, anaphase, and telophase.