define clonal selection
Answers
Answer:
The theory that the mutation of stem cells produces all possible templates for antibody production and that exposure to a specific antigen selectively stimulates the proliferation of the cell with the appropriate template to form a clone or colony of specific antibody-forming cells.
Explanation:
Clonal selection is a part of human immune response where specific B or T-helper lymphocytes are chosen to undergo clonal expansion. B-lymphocytes and T-helper lymphocytes have unique and specific antigen receptors on their cell surface membranes. Each cell will have a slightly different type of antigen receptor
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what is clonal selection Clonal selection Theory of lymphocytes: 1) A hematopoietic stem cell undergoes differentiation and genetic rearrangement to produce 2) immature lymphocytes with many different antigen receptors. Those that bind to 3) antigens from the body's own tissues are destroyed, while the rest mature into 4) inactive lymphocytes. Most of these will never encounter a matching 5) foreign antigen, but those that do are activated and produce 6) many clones of themselves.