Question

Define Michaelis constant of an enzyme.

Answer 1

Medical Definition of Michaelis constant. : a constant that is a measure of the kinetics of an enzymereaction and that is equivalent to the concentration of substrate at which the reaction takes place at one half its maximum rate. Comments onMichaelis constant.

Answer 2

The Michaelis constant is the at which the reaction rate is at half-maximum, and is an inverse measure of the substrate's affinity for the enzyme—as a small indicates high affinity, meaning that the rate will approach with lower than those reactions with a larger .