Question

define thalassemia_??​

Answer 1

Answer:

$\huge{{\mid{\fbox{\tt{QUESTION}}\mid}}}$

define thalassemia_??

$\huge{{\mid{\fbox{\tt{ANSWER}}\mid}}}$

Thalassemia: Thalassemia is a recessive autosomal genetic defect, originated in Mediterranean region caused by mutation or deletion. Thalassemias are a group of disorders caused by defects in the synthesis of globin polypeptide (o and ß chains) in RBC. Absence or reduced synthesis of one of the globin chains results in an excess of the other, hence it is quantitative. In this situation free globin chains, which are insoluble, accumulate inside the red cells and form precipitates which damage the cell, causing cell lysis and resulting in anaemia. There are two main types of thalassemias in which synthesis of a or ß globin is defective. It is common in Mediterranean, Middle East, Indian subcontinent and in south-east Africa.

Answer 2

Answer:

A blood disorder involving lower-than-normal amounts of an oxygen-carrying protein.

Thalassemia is an inherited blood disorder characterised by less oxygen-carrying protein (haemoglobin) and fewer red blood cells in the body than normal.