Describe in brief the reductive amination reactions for synthesis of amino acids in plants.
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Description of the reductive amination reactions for synthesis of amino acids in plants is as follows:
- The reductive amination of alpha-ketoglutarate is catalyzed by glutamate dehydrogenase. It is converted to glutamate.
- In synthesis of amino acids, this reaction occurs.
- Hydroxylation of essential amino acid named phenylalanine synthesizes tyrosine.
- To make RNA and DNA methionine, the required coenzyme is folate.
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Reductive amination reaction: In this reaction transaminase enzyme plays a major role.
Explanation:
- The transaminase enzyme which involves the biosynthesis of many alpha amino acid by the reductive amination reaction of an alpha keto acid.
- The first step is the formation of an imine. This is mainly a coupling reaction the carbonyl group is converted into an amine.
- This reaction forms the basis of many pharmaceutical industry. It first reacts and form a hemiaminal species.
- Thus, reductive amination reaction is explained briefly.
Learn more about Reductive amination reaction:
What is the source of amino group for amino acid synthesis in reductive amination reaction?
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