Describe multiplication phase, growth phase and maturation phase
Answers
I. Multiplication phase:
In this stage, the
primary germinal cells PGCs (2n) of ovary
undergo repeated mitotic division to form
millions of gamete mother cells or oogonial
cells (2n). This process is completed in the
embryonic stage of human females.
II. Growth phase:
Some of the oogonia stop
division and begin to increase in size and form
the primary oocytes (2n). Cellular organelles
like ER, golgi appratus and mitochondria
increase in number.
III. Maturation phase:
Oogenesis takes place
in the ovaries. The process is initiated prior to
birth of the female baby. The primary oocytes
(2n) enter the maturation phase which includes
meiotic division (Meiosis I and Meiosis II).
The diploid primary oocytes undergo meiosis I
(reduction division) to form 2 haploid daughter
cells. This division is peculiar in females
as both the daughter cells are with haploid
number of chromosomes i.e. 23 chromosomes.
But due to unequal division of cytoplasm, of
the 2 daughter cells produced, one is a large
cell called secondary oocyte (n) and another is
a small cell called 1st polar body (n). Normally
the 1st polar body does not enter meiosis II.
The secondary oocyte (n) proceeds meiosis II,
only upto metaphase II. It’s division is further
stopped or arrested at this stage. The secondary
oocyte is shed from the graafian follicle and
ovary. The restart and completion of meiosis II
will happen only with entry of the sperm. This
last phasand is ready for fertilization. (Completion of
meiosis II and completion of fertilization go
hand in hand. If the secondary oocyte does not
receive the sperm / spermatozoa, it is shed off
along with menstrum).
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