Question

Difference between alt and ast liver enzymes

Answer 1

The AST/ALT ratio is the ratio between the concentrations of the enzymesaspartate transaminase (AST) and alanine transaminase (ALT) in the blood of ahuman or animal. It is measured with a blood test and is sometimes useful inmedical diagnosis to differentiate between causes of liver damage, orhepatotoxicity.


Most causes of liver cell injury are associated with a greater increase in ALT than AST; however, an AST to ALT ratio of 2:1 or greater is suggestive of alcoholic liver disease, particularly in the setting of an elevated gamma-glutamyl transferase.

The AST to ALT ratio can also occasionally be elevated in a liver disease pattern in patients with nonalcoholic steatohepatitis, and it is frequently elevated in an alcoholic liver disease pattern in patients with hepatitis C who have developed cirrhosis. In addition, patients with Wilson's disease or cirrhosis due to viral hepatitis may have an AST that is greater than the ALT, though the ratio typically is not greater than two.

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Answer 2

The AST/ALT ratio is the ratio between the concentration of the enzymes aspartate transaminase (AST) n Alaine transaminase (ALT) in the blood of a human or animal. IT is measured with a blood test and is sometimes useful in medical diagnosis to differentiate btwn causes of liver damage or hepatotoxiaty

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