Difference between ciliary epithelium micrornas and aqueous humor micrornas
Answers
Answer:
Aqueous humor (AH) is one of the body fluids in the eye, which is known to be related with various ocular diseases, but the complete RNAs characteristic of the AH in patients is not yet known. The aim of this study was, with a microarray analysis, to reveal the disease-related extracellular miRNAs profiles in individual patients AH. 100 μl of AH was collected by anterior chamber paracentesis from 10 glaucoma, 5 cataract, and 5 epiretinal membrane patients.
Explanation:
Table 1
Patient characteristics, summary of RNA yield and number of miRNAs detected by microarray. POAG : primary open angle glaucoma PEX : pseudoexfoliation glaucoma, PACG : primary angle closure glaucoma
Patient no. Age (years) Sex Preoperative diagnosis Note Amount of total RNA (ng) Number of detected genes
Cont. 1 71 M Cataract Hypertension 6.54 539
Cont. 2 77 M Cataract Dislipidemia, diabetic melllitus 4.59 821
Cont. 3 66 F Cataract Hypertension, dislipidemia 1.43 626
Cont. 4 66 F Cataract 7.33 518
Cont. 5 69 F Cataract Hypertension, dislipidemia, 6.64 432
Cont. 6 69 F Epiretinal Membrane Hypertension 5.81 490
Cont. 7 84 F Epiretinal Membrane Hypertension, dislipidemia, diabetic melllitus 8.47 298
Cont. 8 80 M Epiretinal Membrane Hypertension 7.24 465
Cont. 9 74 F Epiretinal Membrane Hypertension 7.24 395
Cont. 10 55 F Epiretinal Membrane Dislipidemia 6.62 1026
Gla. 1 83 F Glaucoma (POAG), Cataract Hypertension, diabetic melllitus 6.06 602
Gla. 2 64 M Glaucoma (PACG), Cataract 5.56 801
Gla. 3 87 M Glaucoma (POAG), Cataract Hypertension, dislipidemia 6.24 583
Gla. 4 75 F Glaucoma (POAG) Hypertension, dislipidemia 6.64 455
Gla. 5 58 F Glaucoma (PEX) 7.21 519
Gla. 6 70 M Glaucoma (PEX) 3.40 345
Gla. 7 63 M Glaucoma (POAG) Hypertension 2.75 186
Gla. 8 70 M Glaucoma (POAG) Hypertension 7.42 740
Gla. 9 82 M Glaucoma (POAG) Diabetic melllitus 3.48 344
Gla. 10 76 F Glaucoma (POAG) 3.96 425