Question

Difference between frameshift and missense mutation

Answer 1

The main difference between pointmutation and frameshift mutation is that point mutation is an alteration of a single nucleotide in a gene whereasframeshift mutation involves one or more nucleotide changes, altering the open reading frame of a particular gene Point mutations are mainly nucleotide substitutions.

Answer 2

Answer:

• Point mutations happen when there is a replacement of one base pair from another, while Frameshift mutations occur when there is an insertion or deletion of the base pairs from the DNA structure.

• Point mutations occur due to alterations in the single nucleotide, whereas frameshift occurs due to alterations in numerous nucleotides.

• Point mutation brings changes in the structure of a gene because of the substitutions with another base pair, on the contrary, frameshift mutations change the number of nucleotides due to either insertions or deletions of the nucleotides.

Explanation:

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