Chemistry, asked by stylemylo2022, 1 year ago

Difference between isosorbide mononitrate and isosorbide dininitrate

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Answered by akshay77

When ISDN is administered in 3 to 4 doses daily, nitrate tolerance can develop, rendering the agent less efficacious. Isosorbide mononitrate(ISMN) is the active metabolite of ISDN and is primarily used in themanagement of chronic stable angina. ... It has high bioavailability and a longer half-life (4-6 hours) than ISDN.

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