Difference between opioid and nonopioid analgesics tabular form
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They are milder forms of the painkillers. Opioid analgesics are more effective than NSAIDs in providing pain relief. ... Opioids are much stronger and are used when pain signals are too severe to be controlled by non-narcotic analgesics. The primary difference has to do with how drugs produce their analgesic effects.
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Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins, endomorphins and nociceptin. The opioid receptors are ~40% identical to somatostatin receptors.
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