Difference between phosphoester bond and phosphodiester bond
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They are both chemical linkages. For the purposes of an introductory biology class, they are the same thing. Phosphodiester is a more correct way to describe the bonds in nucleic acids like DNA and RNA, but the two terms are sometimes used interchangeably. To a chemist they may not mean exactly the same thing, but in a biology class I think it is safe to ignore the difference and consider them to mean essentially the same thing. If you are writing something for class and you want to use the correct word, use phosphodiester to describe the way that nucleotides are linked together in DNA and RNA.
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phosphoric acid when linked with one molecule of sugar (ribose or deoxyribose) it makes phosphoester linkage but when it is joint to two molecule of sugar ( ribose or deoxyribose ) as we see in the structure of DNA or RNA it is called phosphodiester
hope you understand
*above structure is a rough sketch so please just understand the concept and dont make issue if anything was miss in it
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