Difference in surface markers between monocyte macrophages and dendritic cells
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Dendritic cells (DCs), monocytes and macrophages are members of the mononuclear phagocyte system (MPS) that exhibit multiple functions during immune responses. ... By contrast, DCs are usually defined as cells with a stellate morphology that can efficiently present antigens on MHC molecules and activate naive T cells7,8.
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For example, the cell-surface marker CD68 does not distinguish between macrophages and dendritic cells (Figure 1). ... Although dendritic-cell markers exist, it is also noteworthy that both macrophages and dendritic cells can express major histocompatibility complex class II.
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