Direct translocation from cytosol in protein degradation
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it recognize the eleader sequence of ER lumial protein during translation
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Direct translocation from cytosol in protein degradation:
- Both the "foreign and native proteins" are usually digested into "small peptides" as a part of the "adaptive immune response".
- Proteins are addressed for proteasomal degradation by a two section degron, which comprises of a proteasome binding signal and a degradation initiation site.
- Protein translocation is a method by which proteins drive between cellular subdivision.
- Short amino-acid sequences within a protein, known as signal peptides or signal sequences, can direct its localization, although translocation also occurs in the absence of these signal sequences.
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Anaphase promoting complex us a protein degradation
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