Question

DNA is a polymer of nucleotides which are linked to each other by 3’-5’
phosphodiester bond. To prevent polymerisation of nucleotides, which
of the following modifications would you choose?
a. Replace purine with pyrimidines
b. Remove/Replace 3' OH group in deoxy ribose
c. Remove/Replace 2' OH group with some other group in deoxy
ribose
d. Both ‘B’ and ‘C’


NCERT Class XII
Biology - Main Course Book

Chapter 6. Molecular Basis of Inheritance

Answer 1

To prevent polymerisation of nucleotides,

b. Remove/Replace 3' OH group in deoxy ribose

Answer 2

b. Remove/Replace 3' OH group in deoxy ribose is the answer.