Do we always get microbial growth to confirm cause of disease?
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Manifestations of Infection
The clinical presentation of an infectious disease reflects the interaction between the host and the microorganism. This interaction is affected by the host immune status and microbial virulence factors. Signs and symptoms vary according to the site and severity of infection. Diagnosis requires a composite of information, including history, physical examination, radiographic findings, and laboratory data.
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A pathogen is a micro-organism that has the potential to cause disease. An infection is the invasion and multiplication of pathogenic microbes in an individual or population.
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