Does DNA ligase catalyze phosphodiester bonds between the two strands of DNA (the origianal strand and the new strand) at the end of DNA replication?
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The nicks that remain between the newly-synthesized DNA (that replaced the RNA primer) and the previously-synthesized DNA are sealed by the enzyme DNA ligase that catalyzes the formation of phosphodiester linkage between the 3′-OH end of one nucleotide and the 5′ phosphate end of the other fragment.
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yes the statement is true
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