Question

Does the action of atrial natriuretic peptide (ANP) on mesangial cells change glomerular filtration rate? Does increased release of renin?

Answer 1

Atrial natriuretic peptide (ANP) relaxes the mesangial cells, which are located in the glomerulus of the nephron. This increases pressure in the glomerular capillaries and thus increases the glomerular filtration rate (GFR). Renin is produced in the JG cells of the juxtaglomerular apparatus (juxta = next to)