Ease of abstraction of hydrogen atom from side chain
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Hydrogen atom abstraction or hydrogen atom transfer (HAT) in chemistry is any chemical reaction in which a hydrogen free radical is abstracted from a substrate according to the general equation:
X. + H-Y -> X-H + Y.
Examples of HAT reactions are oxidative reactions in general, hydrocarbon combustion and reactions involving cytochrome P450 containing an iron(V)-oxo unit.
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