Question

Electronic and structural effects on acidity and basicity

Answer 1

Now that we know how to quantify the strength of an acid or base, our next job is to gain an understanding of the fundamental reasons behind why one compound is more acidic or more basic than another. This is a big step: we are, for the first time, taking our knowledge of organic structure and applying it to a question of organic reactivity. Many of the ideas that we’ll see for the first here will continue to apply throughout the book as we tackle many other organic reaction types.