explain about t cells which are immue cells in deatail or brief no spamming pls
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T cells (also called T lymphocytes) are one of the major components of the adaptive immune system. Their roles include directly killing infected host cells, activating other immune cells, producing cytokines and regulating the immune response.
This article shall discuss the production of T cells, the different types present in the immune system and relevant clinical conditions.
Production of T Cells
T cells originate from haematopoietic stem cells which are produced in the bone marrow. Some of these multipotent cells will becomes progenitor cells that leave the bone marrow and travel to the thymus via the blood. In the thymus these cells mature: T cells are named after their thymus-dependent development.
T cells undergo a selection process in the thymus, which the majority of developing T cells (called thymocytes) will not survive. Thymocytes that interact with self-MHC molecules receive positive signals for survival, and thymocytes that have receptors to self-antigen receive negative signals and are removed from the repertoire.
Each T cell will develop its own T cell receptor (TCR) that is specific for a particular antigen. T cells that survive thymic selection will mature and leave the thymus. They will circulate through the peripheral lymphoid organs, each ready to encounter a specific antigen and be activated. Once activated, the T cell will proliferate and differentiate into an effector T cell.
The thymus involutes as we age and so produces fewer naïve T cells over time. This means that older people have reduced T cell diversity, which contributes to the increased susceptibility to infections seen with age.
Answer:T cell, also called T lymphocyte, type of leukocyte (white blood cell) that is an essential part of the immune system. ... T cells are one of two primary types of lymphocytes—B cells being the second type—that determine the specificity of immune response to antigens (foreign substances) in the body.
Tcells (also called T lymphocytes) are one of the major components of the adaptive immune system. Their roles include directly killing infected host cells, activating other immune cells, producing cytokines and regulating the immune response.
T cell: A type of white blood cell that is of key importance to the immune system and is at the core of adaptive immunity, the system that tailors the body's immune response to specific pathogens. The T cells are like soldiers who search out and destroy the targeted invaders.
Underactive regulatory T cells are associated with autoimmune diseases where the immune system attacks the body, including rheumatoid arthritis, multiple sclerosis, inflammatory bowel disease and lupus.
There are 3 main types of T cells: cytotoxic, helper, and regulatory. Each of them has a different role in the immune response. Cytotoxic T cells (Tc cells) have a co-receptor called CD8 on their cell surface. CD8 partners with the T cell receptor and with MHC class I molecules, acting as a sort of bridge.
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