Question

explain denaturation of DNA​

Answer 1

Explanation:

When a DNA solution is heated enough, the double-stranded DNA unwinds and the hydrogen bonds that hold the two strands together weaken and finally break. The process of breaking double-stranded DNA into single strands is known as DNA denaturation, or DNA denaturing.

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Answer 2

Answer:

Explanation:

DNA denaturation refers to the melting of double-stranded DNA to generate two single strands. This involves the breaking of hydrogen bonds between the bases in the duplex. From a thermodynamic point of view, the most important contribution to DNA helix stability is the stacking of the bases on top of one another. Thus, in order to denature DNA, the main obstacle to overcome is the stacking energies that provide cohesion between adjacent base pairs. In general, stacking energies are less for pyrimidine/purine (YR) steps, and for AT-rich regions. Thus, the sequence TATATA would be expected to melt quite readily, and this is indeed what happens, both in a test tube and inside cells.