Explain Heamophilia?
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Heamophilia is a sex linked recessive disease which shows it's transmission from parents to offspring.In this protein which is a part of cascade of proteins is affected.In affected person a simple cut results into non stop bleeding which can ever cause death.
Most frequent asked questions is why there is less chance of becoming a female heamophilic .The answer is because for a female to be affected the mother should be carrier and father should be heamophilic which is unviable in the later stages of life.
The family pedigree of queen Victoria shows a number of hemophilic affected ones as she was the carrier of the disease.
#Hope it helps
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Heamophilia is a sex linked recessive disease which shows it's transmission from parents to offspring.In this protein which is a part of cascade of proteins is affected.In affected person a simple cut results into non stop bleeding which can ever cause death.
Most frequent asked questions is why there is less chance of becoming a female heamophilic .The answer is because for a female to be affected the mother should be carrier and father should be heamophilic which is unviable in the later stages of life.
The family pedigree of queen Victoria shows a number of hemophilic affected ones as she was the carrier of the disease.
#Hope it helps
☆ Follow Me
coolboy2:
thankful to u dost aapne mera har question KA nswer diya hai
no problem bro
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Hemophilia is an inherited disease linked to the X chromosome, i.e it is linked to sex, which means that in the specific case of hemophilia is transmitted by women (carriers) and suffer from men, due to the provision of two chromosomes X (XX) of the woman and an endowment (XY) in the man.
It is caused by an alteration in the genes F8 or F9 producing factor VIII (FVIII) and factor IX (FIX) of coagulation, it is a disease caused by the deficiency of one of these factors in the coagulation system.
The coagulation system works by 13 factors (Factor I, Factor II, Factor III, Factor IV, Factor V, Factor VI, Factor VII, Factor VIII, Factor IX, Factor IX, Factor X, Factor XI, Factor XII and Factor XIII) Which work together in what is called the "coagulation cascade". If one of these factors does not work well, the cascade is discontinued and the clot that prevents bleeding is formed more slowly. As a consequence of this interruption in the coagulation cascade, the lesions or wounds bleed for longer than due, causing internal and external bleeding.
It is a disease that is not contagious and affects 1 in 10,000 babies.
Hope It Helps You!
Hemophilia is an inherited disease linked to the X chromosome, i.e it is linked to sex, which means that in the specific case of hemophilia is transmitted by women (carriers) and suffer from men, due to the provision of two chromosomes X (XX) of the woman and an endowment (XY) in the man.
It is caused by an alteration in the genes F8 or F9 producing factor VIII (FVIII) and factor IX (FIX) of coagulation, it is a disease caused by the deficiency of one of these factors in the coagulation system.
The coagulation system works by 13 factors (Factor I, Factor II, Factor III, Factor IV, Factor V, Factor VI, Factor VII, Factor VIII, Factor IX, Factor IX, Factor X, Factor XI, Factor XII and Factor XIII) Which work together in what is called the "coagulation cascade". If one of these factors does not work well, the cascade is discontinued and the clot that prevents bleeding is formed more slowly. As a consequence of this interruption in the coagulation cascade, the lesions or wounds bleed for longer than due, causing internal and external bleeding.
It is a disease that is not contagious and affects 1 in 10,000 babies.
Hope It Helps You!
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