Explain how fluoroacetate can inhibit the Krebs cycle
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Explanation:
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Fluoroacetate disrupts the citric acid cycle (also known as the Krebs cycle) by combining with coenzyme A to form fluoroacetyl CoA, which reacts with citrate synthase to produce fluorocitrate which binds very tightly to aconitase, thereby halting the citric acid cycle.
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fluoro acetate is one of the molecule which inhibits the crab cycle.
Explanation:
- fluoroacetate reacts with coenzyme a to form fluoroacetyl CoA.
- this molecule then reacts with citric acid synthase enzyme to produce fluoroacetyl citrate.
- The fluro citrate inhibits the aconitase enzyme by tightly attaching to it and resulting in a spatial rearrangement of the molecule. As a result of this the rest of the citric acid cycle stops due to the dearrangement of the molecule.
To know more about krebs cycle
What is Krebs Cycle?Answer Quickly. - Brainly.in
https://brainly.in/question/18135208
krebs cycle is also known as citric acid cycle because - Brainly.in
https://brainly.in/question/4208873
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