Question

Explain mutations and instability of human DNA​

Answer 1

Explanation:

There are three types of DNA Mutations: base substitutions, deletions and insertions.

Base Substitutions. Single base substitutions are called point mutations, recall the point mutation Glu -----> Val which causes sickle-cell disease.

Deletions. ...

Insertions.

Examples of Mutation. Sickle Cell Disease and Malaria. Klinefelter's Calicos. Lactose Tolerance.

Genome instability (also genetic instability or genomic instability) refers to a high frequency of mutations within the genome of a cellular lineage. These mutations can include changes in nucleic acid sequences, chromosomal rearrangements or aneuploidy. Genome instability does occur in bacteria.

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Answer 2

Mutation and Instability:

Genome instability (also genetic instability or genomic instability) refers to a high frequency of mutations within the genome of a cellular lineage. These mutations can include changes in nucleic acid sequences, chromosomal rearrangements or aneuploidy. Genome instability does occur in bacteria.