Explain the B-oxidation of saturated fatty acids. Calculate the ATP generated on complete
oxidation of palmitic acid.
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Oxidation of of palmitic acid yields 7 NADH + 7 FADH2 + 8 acetyl-CoA in 7 cycles of mitochondrial beta oxidation. Every acetyl-CoA yields 3 NADH + 1 FADH2 + 1 GTP (=ATP) during Krebs cycle. Considering an average production of 3 ATP/NADH and 2 ATP/FADH2 using the respiratory chain, you have 131 ATP molecules. However you have to used 2 ATP molecules for the initial activation of every fatty acid that is going to be oxidized in the mitochondria.
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