Question

explain the glycolysis in detail

Answer 1

The essential metabolic pathway of glycolysis involves the oxidative breakdown of one glucose into two pyruvate with the capture of some energy as ATP and NADH. Glycolysis is important in the cell because glucose is the main source of fuel for tissues in the body.  For example, glucose is the only source of energy for the brain. To ensure normal brain function, the body must maintain a constant supply of glucose in the blood. Glycolysis is also important because the metabolism of glucose produces useful intermediates for other metabolic pathways, such as the synthesis of amino acids or fatty acids.  

The major themes to remember when studying glycolysis include:

Glycolysis is a sequence of enzymatic reactions

ATP is invested, then recaptured with a net gain of 2 ATP

Pathway is regulated at key steps when ΔG << 0

Production of useful intermediates for other metabolic pathways

Answer 2

Glycolysis is the metabolic process that serves as the foundation for both aerobic and anaerobic cellular respiration. In glycolysis, glucose is converted into pyruvate. Glucose is a six- memebered ring molecule found in the blood and is usually a result of the breakdown of carbohydrates into sugars. It enters cells through specific transporter proteins that move it from outside the cell into the cell’s cytosol. All of the glycolytic enzymes are found in the cytosol.

The overall reaction of glycolysis which occurs in the cytoplasm is represented simply as:

C6H12O6 + 2 NAD+ + 2 ADP + 2 P —–> 2 pyruvic acid, (CH3(C=O)COOH + 2 ATP + 2 NADH + 2 H+

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