Explain the life cycle of Entamoeba Histolytica.
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✨ Cysts are typically found in formed stool, whereas trophozoites are typically found in diarrheal stool. Infection by Entamoeba histolytica occurs by ingestion of mature cysts
✨in fecally contaminated food, water, or hands. Excystation
✨occurs in the small intestine and trophozoites
✨are released, which migrate to the large intestine. The trophozoites multiply by binary fission and produce cysts
✨and both stages are passed in the feces
✨ Because of the protection conferred by their walls, the cysts can survive days to weeks in the external environment and are responsible for transmission. Trophozoites passed in the stool are rapidly destroyed once outside the body, and if ingested would not survive exposure to the gastric environment.
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Here is u r Ans ➡
✨ Cysts are typically found in formed stool, whereas trophozoites are typically found in diarrheal stool. Infection by Entamoeba histolytica occurs by ingestion of mature cysts
✨in fecally contaminated food, water, or hands. Excystation
✨occurs in the small intestine and trophozoites
✨are released, which migrate to the large intestine. The trophozoites multiply by binary fission and produce cysts
✨and both stages are passed in the feces
✨ Because of the protection conferred by their walls, the cysts can survive days to weeks in the external environment and are responsible for transmission. Trophozoites passed in the stool are rapidly destroyed once outside the body, and if ingested would not survive exposure to the gastric environment.
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Hope This Helps u ☺.
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Entamoeba histolytica is monogenetic in nature, completing its life cycle only in human.
It has 3 stages: Trophozoite, precyst and cystic.
Trophozoite is an active stage where the animal moves like amoeba performing active feeding and growth while other two stages are not harmful. However, cystic stage in tetranucleate condition is infective.
- The trophozoite can reproduce asexually by Binary fission - mitosis followed by cytokinesis. The daughter cells feed on bacteria, grow in size and feed on tissue element to form precyst stage.
- Precyst forms encystment only in lumen of large intestine. They form a round tough cyst wall and nucleus divides inside the cyst form binucleate and then tetranucleate which is a cystic stage. This process complete within hours.
- The tetranucleate cysts passes through stools; remaining alive for 10days. By intake of contaminated food or by vectors it reaches to another human to begin new infection.
- Cyst wall protects it from action of stomach gastric juices, when it reaches the intestine it excyst by action of trypsin within 5-6 hours releasing metacyst.
- Each metacyst grow by binary fission producing 8 metacyst trophozoites. They invade mucus lining and grow in size forming mature trophozoite beginning another cycle.
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