Question

Explain the process of formation of complex proteins

Answer 1

The formation of protein complexes involves an encounter complex, in which proteins show few specific interactions and assume many orientations. Recent kinetic and structural studies have shed light on this elusive state. It is generally dominated by electrostatic interactions, although hydrophobic interactions can play a role. During the encounter phase the proteins remain largely solvated. In extreme cases, the proteins only form an encounter complex, and in many other complexes, the encounter state constitutes a significant amount (5% or more), indicating that the energy difference between encounter and productive complexes is small. Thus, the encounter complex represents an essential part of protein complexes.

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Answer 2

Protein complex is the association of two or more polypeptide chains. Proteins are linked by non-covalent protein-protein interactions to form protein complex. few protiens interact and form orientation, this is named as encounter complex. this encounter complex form electrostatic interaction which provide stability which is dipolarin nature. the stability is maintained by low energy transition, beacuse of which protein get trapped and complex protein is formed.