Question

Finding the difference between periosteal and endocortical bone adaptation using artificial neural network

Answer 1

In silico models of bone adaptation successfully simulated in vivo periosteal bone apposition, however, there are instances where these models may have limited success in predicting the new bone formation at endocortical surface. In vivo studies have highlighted that cortical bone surfaces may have differences in their modeling or remodeling responses to mechanical loading. However, the principle which the two cortical surfaces follow in bone adaptation is not very clear. This work accordingly attempts to understand how periosteal and endocortical surfaces accommodate loading-induced new bone formation. A neural network model is used to serve the purpose.