Question

Foot and Mouth Disease Virus(FMDV) vaccine is made by growing the virus in animal cells, harvesting the virus and inactivating it for vaccine formulations. Given the following data, calculate the weight and volume of the harvested virus from a bioreactor-
(a) Total bioreactor capacity= 1000 l( atleast 20% space must be kept for oxygen and CO2 )
(b) Number of animal cells= 105 /ml
(c) Number of virus particles/animal cell=50
Assume the virus to be a sphere with a gram molecular weight of 106 Daltons (1 million) and radius = 1nm.

Answer 1

Evaluation of the Cavidi ExaVir Load Assay ( Version 3) for Plasma Human Immunodeficiency Virus Type 1 Load Monitoring.

Answer 2

Explanation:

Vaccine formulation is a specialist task that can only be performed by specialists and molecular biologists who understand the scope of the work. There are many large organisations that are into the process and help in making vaccines that help in preventing many types of diseases. The given question is related to making such a vaccine and can be solved according to certain principles and theorems which can be found.