For example, b1-integrin, as one of the most comprehensively-studied integrin subtypes, has been shown to suppress chemotherapy-induced apoptosis, which is commonly found in both hematologic and solid tumors
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1. Int J Cancer. 2010 Sep 1;127(5):1240-8. doi: ... premature senescence and facilitate apoptosis in human ... Glioblastoma are known to be highly resistant to chemotherapy.
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b1-integrin, as one of the most comprehensively-studied integrin subtypes, has been shown to suppress chemotherapy-induced apoptosis, which is commonly found in both hematologic and solid tumors
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