Question

Frequency of autosomal lethal gene is 0.4. No. of carriers in population of 200 individuals will be

Answer 1

The frequency of the recessive allele is q = 0.4 (given)  Hence, p = 1-0.4 = 0.6  (as p = 1- q)  According to Hardy- Weinberg principle,  p2 + ​2pq + q2 = 1.  hnce,         p2 = (0.6)2 => 0.36                    q2 = (0.4)2 => 0.16                2pq = 0.48  since, 2pq is the frequency of hetrozygous carrier,                        = 0.48 X 200                      => 96 Individuals