From which cells of pancreatic islets insulin and glucagon hormone is secreted?
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Pancreatic islets house three major cell types, each of which produces a different endocrine product:
Alpha cells (A cells) secrete the hormone glucagon.
Beta cells (B cells) produce insulin and are the most abundant of the islet cells.
Delta cells (D cells) secrete the hormone somatostatin, which is also produced by a number of other endocrine cells in the body.
Interestingly, the different cell types within an islet are not randomly distributed - beta cells occupy the central portion of the islet and are surrounded by a "rind" of alpha and delta cells. Aside from the insulin, glucagon and somatostatin, a number of other "minor" hormones have been identified as products of pancreatic islets cells.
Explanation:
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The Alpha cells produce glucagen and make up islets 15 to 20 percent and Beta cells produce insulin and amylin and make up 80 percent islets.
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