function of sir explain
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Silent Information Regulator (SIR) proteins are involved in regulating gene expression and some SIR family members are conserved from yeast to humans. SIR proteins organize heterochromatin at telomeres, and at silent loci including, in yeast, the hidden mating type loci.SIR family genes encode catalytic and non-catalytic proteins that are involved in de-acetylation of histone tails and the subsequent condensation of chromatin around a SIR protein scaffold
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