Question

Gabriel phthalimide reaction is used for the preparation of

Answer 1

Gabriel synthesis. The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary amines. Traditionally, thereaction uses potassium phthalimide.

Answer 2

ANSWER:

✔Aromatic amines cannot be prepared by Gabriel Phthalimide synthesis reaction because aryl halides do not undergo nucleophilic substitution with the anion formed by phthalimide.

✔It is used for the preparation of primary aliphatic amines.

✔Phthalimide on treatment with ethanolic potassium hydroxide forms potassium salt of phthalimide which on heating with alkyl halide followed by alkaline hydrolysis produces the corresponding primary amine.