Biology, asked by krishnasajeev8503, 1 year ago

Genome-wide rnai screening identifies protein modules required for 40s subunit synthesis in human cells

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Answered by ItzFruTy07
1

We used an imaging-based, genome-wide RNAi screen to find human proteins involved in 40S ribosomal subunit biogenesis. Our analysis identified ∼ 300 factors, many part of essential protein modules such as the small subunit (SSU) processome, the eIF3 and chaperonin complexes, and the ubiquitin-proteasome system

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