Question

Give molecular aspect of programmed cell death.

Answer 1

Answer:

there are three major form of programmed cell death: apoptosis autophagic cell death, are regulated necrosis (sometimes referred to as necroptosis).

Explanation:

the term "programmed" in this context implies that the dismantling of the cell is regulated by specific genes and involves the activation of specific molecular pathways.

Answer 2

Explanation:

There has been a tendency among cell death researchers to dichotomize cell death into necrosis, which has been viewed as accidental, pathological cell death, and apoptosis, which is considered as genetically programmed and physiological in nature. However, in the most recent incarnation of the Nomenclature Committee on Cell Death set of recommendations, at least 13 different types of cell death are enumerated, and a systematic classification of cell death based on biochemical and functional considerations is presented. (3) Such complexity may seem daunting at first, but it would be a mistake to oversimplify; once we understand the specific signaling pathways underlying cell death in disease or in response to xenogenous agents, for example, nanoparticles, we may devise specific strategies to regulate or mitigate such effects. Oliver Wendell Holmes, Sr., the celebrated poet–physician, once declared “I would not give a fig for the simplicity this side of complexity, but I would give my life for the simplicity on the other side of complexity.” Thus, we must learn to live with complexity, in order to understand how to prevent adverse effects of engineered nanomaterials and to enable the development of nanotechnologies that are safe-by-design.

There are three major forms of programmed cell death: apoptosis, autophagic cell death, and regulated necrosis (sometimes referred to as necroptosis). The term “programmed” in this context implies that the dismantling of the cell is regulated by specific genes and involves the activation of specific molecular pathways. The pathways regulating programmed cell death are, to a large extent, conserved through evolution.